Signaling pathway

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SLU7 Polyclonal Antibody

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Article Number: PD3534
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: SLU7
Application: WB, IHC
Reactivity : Human,Mouse,Rat
MW(Observed) : 65 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000;IHC 1:50-300
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : SLU7 Polyclonal Antibody detects endogenous levels of SLU7 protein.
Gene name : SLU7
Protein Name : Pre-mRNA-splicing factor SLU7
Alias : SLU7;Pre-mRNA-splicing factor SLU7;hSlu7

Database connection:

Organism

Gene ID

SwissProt

Background:

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus . Nucleus speckle . Cytoplasm . Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules. .

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