Signaling pathway

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RFC3 Polyclonal Antibody

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Article Number: PD3779
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: RFC3
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 40 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : RFC3 Polyclonal Antibody detects endogenous levels of RFC3 protein.
Gene name : RFC3
Protein Name : Replication factor C subunit 3
Alias : RFC3;Replication factor C subunit 3;Activator 1 38 kDa subunit;A1 38 kDa subunit;Activator 1 subunit 3;Replication factor C 38 kDa subunit;RF-C 38 kDa subunit;RFC38

Database connection:

Organism

Gene ID

SwissProt

Background:

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus .

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