Signaling pathway

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RARβ Polyclonal Antibody

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Article Number: PD3822
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: RARβ
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 50 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : RARβ Polyclonal Antibody detects endogenous levels of RARβ protein.
Gene name : RARB
Protein Name : Retinoic acid receptor beta
Alias : RARB;HAP;NR1B2;Retinoic acid receptor beta;RAR-beta;HBV-activated protein;Nuclear receptor subfamily 1 group B member 2;RAR-epsilon

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014],

Cell localization : Nucleus . Cytoplasm .; [Isoform Beta-1]: Nucleus.; [Isoform Beta-2]: Nucleus.; [Isoform Beta-4]: Cytoplasm.

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