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PRDM3 Polyclonal Antibody

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Article Number: PD3949
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: PRDM3
Application: WB, IHC, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 18kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : PRDM3 Polyclonal Antibody detects endogenous levels of PRDM3 protein.
Gene name : MECOM
Protein Name : MDS1 and EVI1 complex locus protein MDS1
Alias : MECOM;MDS1;MDS1 and EVI1 complex locus protein MDS1;Myelodysplasia syndrome 1 protein;Myelodysplasia syndrome-associated protein 1

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],

Cell localization : histone deacetylase complex, nucleus, nucleoplasm, cytoplasm, Golgi apparatus, cytosol, aggresome, nuclear speck, intracellular membrane-bounded organelle,

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