Signaling pathway

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NM23-H2 Polyclonal Antibody

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Article Number: PD4546
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: NM23-H2
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 23 kDa
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : NM23-H2 Polyclonal Antibody detects endogenous levels of NM23-H2 protein.
Gene name : NME2
Protein Name : Nucleoside diphosphate kinase B
Alias : NME2;NM23B;Nucleoside diphosphate kinase B;NDK B;NDP kinase B;C-myc purine-binding transcription factor PUF;Histidine protein kinase NDKB;nm23-H2

Database connection:

Organism

Gene ID

SwissProt

Background:

Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010],

Cell localization : Cytoplasm . Cell projection, lamellipodium . Cell projection, ruffle . Colocalizes with ITGB1 and ITGB1BP1 at the edge or peripheral ruffles and lamellipodia during the early stages of cell spreading on fibronectin or collagen but not on vitronectin or laminin substrates. .; [Isoform 1]: Cytoplasm . Cytoplasm, perinuclear region . Nucleus .; [Isoform 3]: Cytoplasm . Cytoplasm, perinuclear region . Nucleus .

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