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Article Number: PD4570
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: Nibrin
Application: WB, IHC, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 95 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : Nibrin Polyclonal Antibody detects endogenous levels of Nibrin protein.
Gene name : NBN
Protein Name : Nibrin
Alias : NBN;NBS;NBS1;P95;Nibrin;Cell cycle regulatory protein p95;Nijmegen breakage syndrome protein 1
Background:
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008],


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