Signaling pathway

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Moesin/Ezrin/Radixin Polyclonal Antibody

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Article Number: PD4826
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Moesin/Ezrin/Radixin
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 67 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Moesin/Ezrin/Radixin Polyclonal Antibody detects endogenous levels of Moesin/Ezrin/Radixin protein.
Gene name : MSN
Protein Name : Moesin
Alias : MSN;Moesin;Membrane-organizing extension spike protein;RDX;Radixin;EZR;VIL2;Ezrin;Cytovillin;Villin-2;p81

Database connection:

Background:

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus. The phosphorylated form is enriched in microvilli-like structures at the apical membrane. Increased cell membrane localization of both phosphorylated and non-phosphorylated forms is observed after thrombin treatment (by similarity). Localizes at the uropods of T lymphoblasts.

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