Signaling pathway

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MMP-8 Polyclonal Antibody

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Article Number: PD4836
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MMP-8
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 55 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : MMP-8 Polyclonal Antibody detects endogenous levels of MMP-8 protein.
Gene name : MMP8
Protein Name : Neutrophil collagenase
Alias : MMP8;CLG1;Neutrophil collagenase;Matrix metalloproteinase-8;MMP-8;PMNL collagenase;PMNL-CL

Database connection:

Organism

Gene ID

SwissProt

Background:

matrix metallopeptidase 8(MMP8) Homo sapiens This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Cell localization : Cytoplasmic granule. Secreted, extracellular space, extracellular matrix . Stored in intracellular granules.

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