Signaling pathway

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MIP-T3 Polyclonal Antibody

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Article Number: PD4866
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MIP-T3
Application: WB, IHC, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 78 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : MIP-T3 Polyclonal Antibody detects endogenous levels of MIP-T3 protein.
Gene name : TRAF3IP1
Protein Name : TRAF3-interacting protein 1
Alias : TRAF3IP1;MIPT3;TRAF3-interacting protein 1;Interleukin-13 receptor alpha 1-binding protein 1;Microtubule-interacting protein associated with TRAF3;MIP-T3

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

function:Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.,similarity:Belongs to the TRAF3IP1 family.,subcellular location:Microtubules.,subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1.,tissue specificity:Ubiquitous.,

Cell localization : Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900). In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268). .

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