Signaling pathway

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Liprin β1 Polyclonal Antibody

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Article Number: PD5038
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Liprin β1
Application: WB, IHC
Reactivity : Human,Mouse
MW(Observed) : 115 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000;IHC 1:50-300
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Liprin β1 Polyclonal Antibody detects endogenous levels of Liprin β1 protein.
Gene name : PPFIBP1
Protein Name : Liprin-beta-1
Alias : PPFIBP1;KIAA1230;Liprin-beta-1;Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1;PTPRF-interacting protein-binding protein 1;hSGT2

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Cell localization : plasma membrane,cell-cell adherens junction,focal adhesion,

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