Signaling pathway

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HDAC6 Polyclonal Antibody

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Article Number: PD5381
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: HDAC6
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 131 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : HDAC6 Polyclonal Antibody detects endogenous levels of HDAC6 protein.
Gene name : HDAC6
Protein Name : Histone deacetylase 6
Alias : HDAC6;KIAA0901;JM21;Histone deacetylase 6;HD6

Database connection:

Organism

Gene ID

SwissProt

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm . Cytoplasm, cytoskeleton . Nucleus . Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules. .

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