Signaling pathway

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GPR56 Polyclonal Antibody

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Article Number: PD5465
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: GPR56
Application: WB, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 78 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : GPR56 Polyclonal Antibody detects endogenous levels of GPR56 protein.
Gene name : GPR56
Protein Name : G-protein coupled receptor 56
Alias : GPR56;TM7LN4;TM7XN1;G-protein coupled receptor 56;Protein TM7XN1

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],

Cell localization : Cell membrane; Multi-pass membrane protein. [ADGRG1 N-terminal fragment]: Secreted. [ADGRG1 C-terminal fragment]: Membrane raft. Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts.

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