Signaling pathway

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ETL Polyclonal Antibody

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Article Number: PD5785
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ETL
Application: WB, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 77 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : ETL Polyclonal Antibody detects endogenous levels of ETL protein.
Gene name : ELTD1
Protein Name : EGF latrophilin and seven transmembrane domain-containing protein 1
Alias : ELTD1;ETL;EGF;latrophilin and seven transmembrane domain-containing protein 1;EGF-TM7-latrophilin-related protein;ETL protein

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

developmental stage: Up-regulated in the adult heart. domain: The transmembrane domain is not required for cleavage, but it is required for dimer formation. function: Could be involved in cardiac development. PTM: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. similarity: Contains 1 GPS domain. similarity: Contains 2 EGF-like domains. subunit: Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface. tissue specificity: Mainly expressed in smooth muscle.

Cell localization : Cell membrane ; Multi-pass membrane protein .

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