Signaling pathway

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ERCC4 Polyclonal Antibody

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Article Number: PD5802
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ERCC4
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 103 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : ERCC4 Polyclonal Antibody detects endogenous levels of ERCC4 protein.
Gene name : ERCC4
Protein Name : DNA repair endonuclease XPF
Alias : ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009],

Cell localization : Nucleus . Chromosome . Localizes to sites of DNA damage. .

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