Signaling pathway

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ERAP1 Polyclonal Antibody

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Article Number: PD5810
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ERAP1
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 107 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : ERAP1 Polyclonal Antibody detects endogenous levels of ERAP1 protein.
Gene name : ERAP1
Protein Name : Endoplasmic reticulum aminopeptidase 1
Alias : ERAP1;APPILS;ARTS1;KIAA0525;Endoplasmic reticulum aminopeptidase 1;ARTS-1;Adipocyte-derived leucine aminopeptidase;A-LAP;Aminopeptidase PILS;Puromycin-insensitive leucyl-specific aminopeptidase;PILS-AP;Type 1 tumor necrosis facto

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010],

Cell localization : Endoplasmic reticulum membrane ; Single-pass type II membrane protein .

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