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DOCK 180 Polyclonal Antibody

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Article Number: PD5993
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: DOCK 180
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 215 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : DOCK 180 Polyclonal Antibody detects endogenous levels of DOCK 180 protein.
Gene name : DOCK1
Protein Name : Dedicator of cytokinesis protein 1
Alias : DOCK1; Dedicator of cytokinesis protein 1; 180 kDa protein downstream of CRK; DOCK180

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

Cell localization : Cytoplasm . Membrane . Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate. .

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