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COL2A1 Polyclonal Antibody

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Article Number: PD6320
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Collagen II
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 140 kD
Host Species: Rabbit
Isotype : IgG

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Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : COL2A1 Polyclonal Antibody detects endogenous levels of COL2A1 protein.
Gene name : COL2A1
Protein Name : Collagen alpha-1(II) chain
Alias : COL2A1;Collagen alpha-1;II;chain;Alpha-1 type II collagen

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Secreted, extracellular space, extracellular matrix .

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