Signaling pathway

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Choactase Polyclonal Antibody

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Article Number: PD6423
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Choactase
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 82.70 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Choactase Polyclonal Antibody detects endogenous levels of Choactase protein.
Gene name : CHAT
Protein Name : Choline O-acetyltransferase
Alias : CHAT;Choline O-acetyltransferase;CHOACTase;ChAT;Choline acetylase

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],

Cell localization : nucleus, cytoplasm, cytosol, presynapse,

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