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Article Number: PD6423
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: Choactase
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 82.70 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : Choactase Polyclonal Antibody detects endogenous levels of Choactase protein.
Gene name : CHAT
Protein Name : Choline O-acetyltransferase
Alias : CHAT;Choline O-acetyltransferase;CHOACTase;ChAT;Choline acetylase
Background:
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],


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