Signaling pathway

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CEP350 Polyclonal Antibody

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Article Number: PD6457
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: CEP350
Application: IHC, IF, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 351 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:40,000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : CEP350 Polyclonal Antibody detects endogenous levels of CEP350 protein.
Gene name : CEP350
Protein Name : Centrosome-associated protein 350
Alias : CEP350;CAP350;KIAA0480;GM133;Centrosome-associated protein 350;Cep350;Centrosome-associated protein of 350 kDa

Database connection:

Organism

Gene ID

SwissProt

Background:

centrosomal protein 350(CEP350) Homo sapiens The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body . Associated with mitotic spindles (PubMed:16314388). Nuclear, in discrete foci. Associated with intermediate filaments (PubMed:15615782). Also present in the pericentrosomal area (PubMed:17878239). Localizes on both mother and daughter centrioles. Localizes to an axial position on the mother centriole (PubMed:28625565). Localizes to the distal end of the centriole on the subdistal appendage region (PubMed:28659385). .

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