Signaling pathway

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CA XII Polyclonal Antibody

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Article Number: PD6685
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: CA XII
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 40 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC: 100-300; WB 1:500-1:2000; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : CA XII Polyclonal Antibody detects endogenous levels of CA XII protein.
Gene name : CA12
Protein Name : Carbonic anhydrase 12
Alias : CA12;Carbonic anhydrase 12;Carbonate dehydratase XII;Carbonic anhydrase XII;CA-XII;Tumor antigen HOM-RCC-3.1.3

Database connection:

Organism

Gene ID

SwissProt

Background:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014],

Cell localization : Membrane; Single-pass type I membrane protein. Cell membrane .

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