Signaling pathway

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BMP-8 Polyclonal Antibody

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Article Number: PD6752
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: BMP-8
Application: IHC, IF, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 45 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:40,000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : BMP-8 Polyclonal Antibody detects endogenous levels of BMP-8 protein.
Gene name : BMP8A/BMP8B
Protein Name : Bone morphogenetic protein 8A/B
Alias : BMP8B;BMP8;Bone morphogenetic protein 8B;BMP-8;BMP-8B;Osteogenic protein 2;OP-2;BMP8A;Bone morphogenetic protein 8A;BMP-8A

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],

Cell localization : Secreted .

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