Signaling pathway

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BMP-5 Polyclonal Antibody

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Article Number: PD6754
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: BMP-5
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse
MW(Observed) : 52 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : BMP-5 Polyclonal Antibody detects endogenous levels of BMP-5 protein.
Gene name : BMP5
Protein Name : Bone morphogenetic protein 5
Alias : BMP5;Bone morphogenetic protein 5;BMP-5

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016],

Cell localization : Secreted.

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