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Article Number: PD6933
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: ARF GAP1
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat,Monkey,Bovine
MW(Observed) : 48 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : ARF GAP1 Polyclonal Antibody detects endogenous levels of ARF GAP1 protein.
Gene name : ARFGAP1
Protein Name : ADP-ribosylation factor GTPase-activating protein 1
Alias : ARFGAP1;ARF1GAP;ADP-ribosylation factor GTPase-activating protein 1;ARF GAP 1;ADP-ribosylation factor 1 GTPase-activating protein;ARF1 GAP;ARF1-directed GTPase-activating protein
Database connection:
Background:
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],


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