Signaling pathway

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Adducin α/β Polyclonal Antibody

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Article Number: PD7081
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Adducin α/β
Application: WB, IHC, IP, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 80 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Adducin α/β Polyclonal Antibody detects endogenous levels of Adducin α/β protein.
Gene name : ADD1/ADD2
Protein Name : Alpha-adducin/Beta-adducin
Alias : ADD1;ADDA;Alpha-adducin;Erythrocyte adducin subunit alpha;ADD2;ADDB;Beta-adducin;Erythrocyte adducin subunit beta

Database connection:

Background:

adducin 1(ADD1) Homo sapiens Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

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