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SSB (phospho Ser366) Polyclonal Antibody

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Article Number: PF0973
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: SSB
Application: WB, IHC, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 47 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Phospho-SSB (S366) Polyclonal Antibody detects endogenous levels of SSB protein only when phosphorylated at S366.
Gene name : SSB
Protein Name : Lupus The protein
Alias : SSB; Lupus A protein; The autoantigen; The ribonucleoprotein; Sjögren syndrome type B antigen; SS-B

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Sjogren syndrome antigen B(SSB) Homo sapiens The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014],

Cell localization : Nucleus .

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