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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PF1136
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： CaMKIIβ/γ/δ
Application： IF, WB, IHC, ELISA
Reactivity ： Human,Mouse,Rat
MW(Observed) ： 50 kD, 65 kD
Host Species： Rabbit
Isotype ： IgG
隐藏域元素占位
Detailed Information
Modify-Modification ： Phospho
Recommended dilution ratio ： IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;Not yet tested in other applications;
Compose ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Concentration ： 1 mg/ml
Clonality ： Polyclonal
Antigen & Target Information
Specificity ： Phospho-CaMKIIβ/γ/δ (T287) Polyclonal Antibody detects endogenous levels of CaMKIIβ/γ/δ protein only when phosphorylated at T287.
Gene name ： CAMK2B
Protein Name ： Calcium/calmodulin-dependent protein kinase type II subunit beta
Alias ： CAMK2B;CAM2;CAMK2;CAMKB;Calcium/calmodulin-dependent protein kinase type II subunit beta;CaM kinase II subunit beta;CaMK-II subunit beta;CAMK2G;CAMK;CAMK-II;CAMKG;Calcium/calmodulin-dependent protein kinase type II subunit gamma;
Database connection:
Organism
Gene ID
SwissProt
Mouse
Background：
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
Cell localization ： Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . In slow-twitch muscle, evenly distributed between longitudinal SR and junctional SR.
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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