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Article Number: PF1160
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: PAK1
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat,Monkey
MW(Observed) : 61 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : Phospho-PAKα (S199) Polyclonal Antibody detects endogenous levels of PAKα protein only when phosphorylated at S199.
Gene name : PAK1
Protein Name : Serine/threonine-protein kinase PAK 1
Alias : PAK1;Serine/threonine-protein kinase PAK 1;Alpha-PAK;p21-activated kinase 1;PAK-1;p65-PAK
Background:
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],


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