Signaling pathway

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ACTR1B Rabbit mAb

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Article Number: PL0858
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ACTY
Application: WB, IHC, IF, ICC, FC, IP
Reactivity : Human
MW(Observed) : 41 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:1000-5000; IHC 1:100-300; ICC/IF 1:100-300; FC 1:100-300; IP 1:50-100
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0778R

Antigen & Target Information

Specificity : Endogenous
Gene name : ACTR1B;CTRN2
Protein Name : Beta-centractin;Actin-related protein 1B;ARP1B;
Alias : ACTR1B;CTRN2;Beta-centractin ;Actin-related protein 1B;ARP1B;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],

Cell localization : Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

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