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EF-1 α1/2 (Acetyl Lys41) Polyclonal Antibody

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Article Number: PS0269
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: EF-1 α1/2
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 50 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Acetyl
Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Acetyl-EF-1 α1/2 (K41) Polyclonal Antibody detects endogenous levels of EF-1 α1/2 protein only when acetylated at K41.
Gene name : EEF1A1/EEF1A2/EEF1A1P5
Protein Name : Elongation factor 1-alpha 1/Elongation factor 1-alpha 2/Putative elongation factor 1-alpha-like 3
Alias : EEF1A1;EEF1A;EF1A;LENG7;Elongation factor 1-alpha 1;EF-1-alpha-1;Elongation factor Tu;EF-Tu;Eukaryotic elongation factor 1 A-1;eEF1A-1;Leukocyte receptor cluster member 7;EEF1A2;EEF1AL;STN;Elongation factor 1-alpha 2;EF-1-alpha-2;Eukaryotic elongation factor 1 A-2;eEF1A-2;Statin-S1;EEF1A1P5;EEF1AL3;Putative elongation factor 1-alpha-like 3;EF-1-alpha-like 3;Eukaryotic elongation factor 1 A-like 3;eEF1A-like 3;Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm . Nucleus . Nucleus, nucleolus . Cell membrane . Colocalizes with DLC1 at actin-rich regions in the cell periphery (PubMed:19158340). Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens (PubMed:8650580). Localization at the cell membrane depends on EEF1A1 phosphorylation status and the presence of PPP1R16B (PubMed:26497934). .

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