Signaling pathway

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CD141 (PT1650R) PT™ Rabbit mAb

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Article Number: PL0138
Delivery time: 现货
Price: 100 μL/1800
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Target: CD141
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human
MW(CalcμLated) : 95 kD
MW(Observed) : 105 kD
Host Species: Rabbit
Isotype : IgG, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : Monoclonal

Antigen & Target Information

Specificity : Endogenous
Gene name : THBD
Protein Name : Thrombomodulin
Alias : THBD;THRM;Thrombomodulin;TM;Fetomodulin;CD antigen CD141

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],

Cell localization : Membrane; Single-pass type I membrane protein.

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