Signaling pathway

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MARCKS (PT1586R) PT™ Rabbit mAb

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Article Number: PL0191
Delivery time: 现货
Price: 100 μL/1800
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Target: MARCKS
Application: WB, IHC, IF, ELISA
Reactivity : Human
MW(CalcμLated) : 31 kDa
MW(Observed) : 80 kD
Host Species: Rabbit
Isotype : IgG, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : Monoclonal

Antigen & Target Information

Specificity : Endogenous
Gene name : MARCKS
Protein Name : Myristoylated alanine-rich C-kinase substrate
Alias : MARCKS;MACS;PRKCSL;Myristoylated alanine-rich C-kinase substrate;MARCKS;Protein kinase C substrate;80 kDa protein, light chain;80K-L protein;PKCSL

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor .

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