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Article Number: PL0198
Delivery time: 现货
Price: 100 μL/1800
Category:
Target: COX IV
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 20 kD
MW(Observed) : 17 kD
Host Species: Rabbit
Isotype : IgG, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : Monoclonal
Antigen & Target Information
Specificity : Endogenous
Gene name : COX4I1
Protein Name : Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Alias : COX4I1;COX4;Cytochrome c oxidase subunit 4 isoform 1, mitochondrial;Cytochrome c oxidase polypeptide IV;Cytochrome c oxidase subunit IV isoform 1;COX IV-1
Database connection:
Background:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes


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