Product Services
Signaling pathway
-
-
-
Neurodegeneration—A Common Pathway Across Multiple Diseases (0)
-
The AGE–RAGE signaling pathway in diabetic complications (0)
-
PD-L1 Expression and the PD-1 Checkpoint Pathway in Cancer (0)
-
Epithelial Cell Signaling in Helicobacter pylori Infection (0)
-
Glioma-associated Kaposi’s sarcoma-associated herpesvirus infection (0)
Contact Us
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PL0506
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target： Transglutaminase 2
Application： WB, IHC, IF, IP, ELISA
Reactivity ： Human,Mouse
MW(CalcμLated) ： 77 kD
MW(Observed) ： 77 kD
Host Species： Rabbit
Isotype ： IgG, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： Protein A
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： PT1256R
Antigen & Target Information
Specificity ： Endogenous
Gene name ： TGM2
Protein Name ： Protein-glutamine gamma-glutamyltransferase 2
Alias ： TGM2;Protein-glutamine gamma-glutamyltransferase 2;Tissue transglutaminase;Transglutaminase C;TG;C;TGC;TGase C;Transglutaminase H;TGase H;Transglutaminase-2;TGase-2
Background：
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Cell localization ： Catalytic activity: Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3)., cofactor: Binds 1 calcium ion per subunit., Disease: Defects in TGM2 are involved in early-onset diabetes type 2., Function: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins., Induction: By retinoic acid., Online information: Tissue transglutaminase entry, Similarity: Belongs to the transglutaminase superfamily. Transglutaminase family., Subunit: Monomer.,
Recommended
Relevant Literature
We remain open to communication and look forward to supporting you.
Centered on our primary and secondary antibody products, we have established a strong foothold in the specialized antibody reagent market. Leveraging our independently developed core technology platform and a dedicated R&D and manufacturing team, we provide high‑reliability biological reagents and end‑to‑end technical solutions to universities, research institutes, biopharmaceutical companies, and other customers worldwide.
Support Services. Since its inception, Pinofibio has remained committed to a development philosophy centered on research needs. Through a robust R&D system, stringent quality control, and responsive, efficient service, the company is dedicated to building an antibody product portfolio that spans multiple species and targets, helping researchers overcome technical challenges and driving innovation in the biopharmaceutical industry.
Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Xiaohongshu
Experimental Services
Official Account
Antibody Services
微信客服