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Article Number: PL0614
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: Glyt2
Application: World Bank
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 88 kDa
MW(Observed) : 88 kDa
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:1000-1:5000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : PT1132R
Antigen & Target Information
Specificity : Endogenous
Gene name : SLC6A5, GLYT2, NET1
Protein Name : Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)
Alias : GLYT2 NET1
Database connection:
Background:
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]


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