Signaling pathway

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MYL9 (Phospho Thr18/Ser19) Rabbit mAb

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Article Number: PL0988
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Myosin Light Chain 2
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 20 kD
MW(Observed) : 20 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Phospho

隐藏域元素占位

Detailed Information

Modify-Modification : Thr18/Ser19
Recommended dilution ratio : IHC 1:50-1:400; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0752R

Antigen & Target Information

Specificity : MYL9 (Phospho Thr18/Ser19) Antibody detects endogenous levels of MYL9 protein only when phosphorylated at Thr18/Ser19. The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RAtsNV
Gene name : MYL9
Protein Name : Myosin regulatory light polypeptide 9
Alias : MYL9;MLC2;MRLC1;MYRL2;Myosin regulatory light polypeptide 9;20 kDa myosin light chain;LC20;MLC-2C;Myosin RLC;Myosin regulatory light chain 2;smooth muscle isoform;Myosin regulatory light chain 9;Myosin regulatory light chain MRL

Database connection:

Organism

Gene ID

SwissProt

Background:

Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts. .

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