Signaling pathway

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AFP Rabbit mAb

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Article Number: PL1027
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: AFP
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 68 kD
MW(Observed) : 65 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0713R

Antigen & Target Information

Specificity : Endogenous
Gene name : AFP
Protein Name : Alpha-1-Fetoprotein(AFP)
Alias : AFP;HPAFP;Alpha-fetoprotein;Alpha-1-fetoprotein;Alpha-fetoglobulin

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008],

Cell localization : Secreted.

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