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Article Number: PL1050
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: IL-1β
Application: WB, IF, IP, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 31 kDa
MW(Observed) : 31 kDa
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0689R
Antigen & Target Information
Specificity : Endogenous
Gene name : IL1B IL1F2
Protein Name : Interleukin-1 beta (IL-1 beta) (Catabolin)
Alias : IL1B;IL1F2;Interleukin-1 beta;IL-1 beta;Catabolin
Background:
interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],


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