Signaling pathway

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Syk Rabbit mAb

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Article Number: PL1245
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Syk
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 72 kD
MW(Observed) : 65 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:400-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0468R

Antigen & Target Information

Specificity : Endogenous
Gene name : SYK
Protein Name : Tyrosine-protein kinase SYK
Alias : SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Cell localization : Membrane

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