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Article Number: PL1455
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: CD105 (Endoglin)
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,
MW(CalcμLated) : 70 kD
MW(Observed) : 95 kD
Host Species: Rabbit
Isotype : IgG, Kappa
Conjugate : Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:100-200; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT0152R
Antigen & Target Information
Specificity : Endogenous
Gene name : ENG END
Protein Name : Endoglin (CD antigen CD105)
Background:
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],


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