Signaling pathway

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Fascin (ABT-FASN) mouse mAb

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Article Number: PH0261
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Fascin
Application: IHC, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 55 kD
MW(Observed) : 55 kD
Host Species: Mouse
Isotype : IgG1, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-400; ELISA 1:500-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : ABT-FASN

Antigen & Target Information

Specificity : The antibody can specifically recognize human Fascin protein.
Gene name : FSCN1 FAN1 HSN SNL
Protein Name : Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],

Cell localization : Cytoplasmic

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