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Article Number: PD4695
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: Na+ CP type IIα
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 228 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : Na+ CP type IIα Polyclonal Antibody detects endogenous levels of Na+ CP type IIα protein.
Gene name : SCN2A
Protein Name : Sodium channel protein type 2 subunit alpha
Alias : SCN2A;NAC2;SCN2A1;SCN2A2;Sodium channel protein type 2 subunit alpha;HBSC II;Sodium channel protein brain II subunit alpha;Sodium channel protein type II subunit alpha;Voltage-gated sodium channel subunit alpha Nav1.2
Background:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],


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