Signaling pathway

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Na+ CP type IIα Polyclonal Antibody

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Article Number: PD4695
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Na+ CP type IIα
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 228 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Na+ CP type IIα Polyclonal Antibody detects endogenous levels of Na+ CP type IIα protein.
Gene name : SCN2A
Protein Name : Sodium channel protein type 2 subunit alpha
Alias : SCN2A;NAC2;SCN2A1;SCN2A2;Sodium channel protein type 2 subunit alpha;HBSC II;Sodium channel protein brain II subunit alpha;Sodium channel protein type II subunit alpha;Voltage-gated sodium channel subunit alpha Nav1.2

Database connection:

Organism

Gene ID

SwissProt

Background:

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane ; Multi-pass membrane protein .

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