Signaling pathway

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MYO15 Polyclonal Antibody

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Article Number: PG7801
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MYO15
Application: IHC,IF
Reactivity : Human,Mouse
MW(Observed) : 388kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:50-300; IF 1:50-200
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : MYO15 Polyclonal Antibody detects endogenous levels of protein.
Gene name : MYO15A MYO15
Protein Name : Unconventional myosin-XV (Unconventional myosin-15)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008],

Cell localization : Cell projection, stereocilium . Cytoplasm, cytoskeleton . Localizes to stereocilium tips in cochlear and vestibular hair cells. .

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